did doctors use to prescribe cigarettes Tobacco companies ran ads with in white coats claiming 'soothe the throat' and 'aid digestion.' The medical establishment didn't seriously push back until the 1964 Surgeon General report. A full When Smoking Was Just What

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N-acetylcysteine increases the frequency of bone marrow pro-B/pre-B cells, but does not reverse cigarette smoking-induced loss of this subset

Updated: 4:35 PM EST Feb 5, 2014 Editorial Standards Advertisement

40 smokers of conventional cigarettes, 40 exclusive heat-not-burn cigarette users, and 40 non-smokers with similar age and sex who were medical personnel in a university hospital were included in the study

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Allocation concealment Randomisation to experimental condition was automated by the online system and was not accessible to any member of the research team, ensuring good allocation concealment