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Nicotine from ZYNs can inhibit the histone-to-protamine transition in sperm, thereby reducing sperm motility and increasing the number of abnormal sperm
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As the body does with alcohol, caffeine, or other drugs, it can interpret high doses as toxic, resulting in dizziness, nausea, and vomiting. On top of increasing the activity of the central nervous system, nicotine makes users more prone to cardiovascular issues by narrowing and stiffening blood vessels
Establishes the presence of NNAL and NNAL-Glucs in the urine of non-smoking women exposed to environmental tobacco smoke at home, and relates the amounts of these to those in their smoking spouses
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