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Mol Biol Evol 28, 27312739, doi: 10.1093/molbev/msr121 (2011)

Both groups have close links to the tobacco industry and focus their efforts on trying to persuade the government not to raise taxes on tobacco

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However, they pose greater risks if not handled properly, and are best suited for experienced vapers who want to build custom coils and maximize vapor production

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Sustained activation of this pathway promotes inhibition of autophagy, metabolic reprogramming, and increased protein synthesis, thereby reinforcing senescence-associated phenotypes and contributing to the development of a proinflammatory and profibrotic microenvironment [112]