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tax e-cigarettes on a percentage of the wholesale price in order to apply across a wide variety of products and sizes, while others, including Delaware, North Carolina, Kansas, Louisiana, and West Virginia tax per milliliter of nicotine liquid

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We used an adaptive design, which means that part-way through data collection, an interim analysis was conducted to assess how many more participants would need to be recruited for the study to have enough statistical power to detect an effect of pack size