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The source of the ROS might differ in the early, intermediate and late stages of obesity, switching from NOX4-dependence in the early phases to NOX2-dependence, in the intermediate phase, and transiting to mitochondria-dependence later in the time course of obesity

Case presentation A 58-year-old female presented to our emergency department in a wheelchair with severe pitting edema and pain in both lower extremities as well as oliguria after a suicidal attempt that she took vildagliptin 1,400 mg (14-times the normal dosage)

2 Frid AH, Hirsch L, Menchior AR, et al