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This subscale was approved with 9 questions, CVR 0.6 to 1, CVI 0.78 to 1, regression coefficient (factor loading) 0.490 to 0.841, Cronbachs alpha 0.890, and Omega McDonald 0.892

Efficacy of doses lower than 0.5 mg bid have not been reported for any population, thus participants who do not tolerate the dose of varenicline or placebo 0.5 mg bid will be discontinued from medication, but retained in the study and included in the intent-to-treat analyses

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