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Scholar Jordan Goodman comments: From whom Rolfe acquired his seeds is unknown though there was contact between Virginia and Trinidad through English merchants and seamenAny of the considerable number of English and Dutch traders plying around Trinidad and the Orinoco delta and landing in Virginia could have conveyed the seeds to Rolfe

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Inflammation, hypercoagulability and blood viscosity are known to contribute to the initiation and propagation of atherosclerosis and may aggravate the progress of PAD [9,10,11]

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