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Nicotine, a prominent compound in cigarettes, while not carcinogenic, induces chemical addiction 4 and altered tissue physiology, especially vascular regulation

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Nursing Mothers : Bupropion and its metabolites are secreted in human milk Pediatric Use : The safety and efficacy in a pediatric smoking population have not been established Although generally well tolerated, the limited exposure is insufficient to assess the safety of bupropion in pediatric patients