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Cancer Antioxidant Hijacking: Tumors ramp up antioxidant systems to handle high metabolic rates and survive stress including metastasis
It is unclear to what extent the reduction in lean mass is attributable to loss of skeletal muscle mass per se, which comprises only one component of total body lean mass in mice, but the lack of effect on fat mass is consistent with the reported paucity of IGF-1Rs on mature adipocytes
It increases the tone of the detrusor urinae muscle , usually producing a contraction sufficiently strong to initiate micturition and empty the bladder It stimulates gastric motility , increases gastric tone, and often restores impaired rhythmic peristalsis Because of the selective action of bethanechol, nicotinic symptoms of cholinergicstimulation are usually absent or minimal bethanechol is not hydrolyzed by cholinesterase enzymes, resulting in a longer duration of action compared to acetylcholine and other enzyme-sensitive choline esters FDA Approved Indications: To promote emptying of the urinary bladder, including: (but rarely used) Postoperative urinary retention (POUR) Postpartum nonobstructive urinary retention Neurogenic atony of the urinary bladder with retention of urine
