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How chewing tobacco accelerates cancer Chewing tobacco contains multiple carcinogens, including tobacco-specific nitrosamines (TSNAs), which are among the most potent cancer-causing substances found in tobacco, according to cancer.gov

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Cancer can be described as the uncontrolled growth of abnormal cells

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Such lesions typically occur in the buccal or labial vestibule where the tobacco is held, but they can also extend onto the adjacent gingiva and buccal mucosa