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While tobacco-free nicotine products are available, their long-term effect is not yet certain

Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers

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PMID 31133009

While nicotine is not present in some e-liquids, other chemicals within e-liquids such as Formaldehyde (found in many household products), Acrolein (created when glycerol is burned), and Benzene (used in lubricants), can still have negative effects on the body

It is an important concession for those concerned that, in outlawing the cigarette overwhelmingly favored by Black Americans, the change could increase potentially perilous contacts between users of black market menthol products and law enforcement