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According to the CDC, Smoking heart arteries blood vessels Nicotine causes blood vessels to tighten, which restricts the flow of blood

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Kymberle Sterling, the associate director for justice, equity, diversity, and inclusion at the Rutgers Institute for Nicotine and Tobacco Studies, will lead two studies funded by the National Institute on Minority Health and Health Disparities and the National Institute on Drug Abuse

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Source: Imperial Tobacco

They also occasionally speak Romany on the show to each other