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Thus, while hyperpolarization takes place in both ionocyte-depleted KO cultures, the response to electrically mediated depolarization is dampened in PNEC-low POU2F3 KO cultures and exaggerated in PNEC-high FOXI1 KO cultures, revealing an important contribution of PNECs to airway epithelial ion transport function

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Unfortunately only modest smoking cessation rates have been reported in asthma 18,19

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But nicotine addiction is not an innocuous and benign thing