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The habit promotes the development of atherosclerosis, a condition where plaque builds up inside the arteries, leading to hardened and narrowed arteries

It also predisposes individuals who chew tobacco to start smoking which further increase their risk of developing other cancers

The study included a group of e-cigarette users, who had been using them for an average of around 17 months, and measured the levels of nicotine and 26 potentially harmful chemicals in their body, by looking at samples of their urine and saliva

The author (Koufman) examined the reflux testing (pH-monitoring) data of 750 known (smoking and non-smoking) reflux patients and showed that reflux was twice as severe in smokers