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However, prolonged inflammation impairs the microglial cells' ability to bind and phagocytose A, diminishes the activity of A-degrading enzymes, and weakens their capacity to disintegrate A plaques [199, 200]

doi: 10.1016/j.freeradbiomed.2021.07.023

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Full-length human growth hormone represents the central mediator of this axis and is commonly used in research to examine direct growth hormone receptor activation and downstream signaling networks such as JAK2/STAT pathways

For instance, in cardiomyocytes, mitochondrial impairment may primarily disrupt energy production essential for cardiac contraction, while in neurons, it can lead to synaptic dysfunction and neurodegeneration [32]

Hydrogels: an overview of its classifications, properties, and applications