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Tobacco-specific nitrosamines (TSNAs) such as N-nitrosonornicotine (NNN) and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK) have been previously characterized in the vapors of e-cigarettes [35]

However, the study revealed different mechanisms by which tobacco smoking causes these mutations, depending on the area of the body affected

The same goes for menthol

Its adult daily smoking rate fell from 22.3% in 2001 to 14.7% in 2015

What is so exciting about our study is that it shows that its never too late to quit some of the people in our study had smoked more than 15,000 packs of cigarettes over their life, but within a few years of quitting many of the cells lining their airways showed no evidence of damage from tobacco. This research is part of the 20 million Mutographs of Cancer project, a Cancer Research UK Grand Challenge initiative