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Tobacco smoking reduces p53, a tumor suppressor gene that is considered the genome guardian. Suppression of T-cell responses by Nicotine and tar is associated with decreased surveillance for tumor cells] reported that heavy smokers accumulate excess iron in hepatocytes which induces fibrosis and favors the development of HCC

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Congress gave the FDA the power to regulate key aspects of the tobacco industry in 2009, including designating new tobacco products as "modified risk," compared with traditional cigarettes, chew and other products

This stubborn myth, however, continues to do the rounds, even among long-term smokers and some health professionals