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Curr Pharm Des 20(22):35793594 Kiowski W et al (1994) Diminished vascular response to inhibition of endothelium-derived nitric oxide and enhanced vasoconstriction to exogenously administered endothelin-1 in clinically healthy smokers

Step 3: Gradual Transition Switching cold turkey works for some people, but a gradual approach is safer and often more successful

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