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In healthy individuals, blood vessels tighten to maintain blood flow to the brain, but in people with OI this response is impaired, leading to dizziness, lightheadedness, fatigue, brain fog, palpitations, and occasional fainting

doi:10.1371/journal.pone.0227837

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As tolerance builds, the brain requires nicotine simply to function at baseline

Most cruise lines allow you to book through them, which is a good idea, as it ensures you will be returned to your ship in time for departure.