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[43] Clonidine may reduce withdrawal symptoms and "approximately doubles abstinence rates when compared to a placebo," but its side effects include dry mouth and sedation, and abruptly stopping the drug can cause high blood pressure and other side effects

Orwell's bed-wetting at age eight was treated as a crime punishable by beating, instilling deep shame and a sense of being inherently wicked

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Afraid that being seen buying them would hurt his King of Cool persona, he often had his friend and frequent collaborator Jerry Lewis buy them for him