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For the meta-analysis, the exposure variables were ever e-cigarette use (yes/no) and past 30-day e-cigarette use status (1 day or more versus 0)

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Consume entire drink within 10-15 minutes

Mice exposed to either EC vapor or air were exposed to Streptococcus pneumoniae , with EC vapor-exposed mice demonstrating a significant decrease in pulmonary bacterial clearance

()- N -nitroso-nornicotine (NNN), ()-NNN-d 4 (2,4,5,6-tetradeutero-(5-(1-nitroso-2-pyrrolidinyl))-pyridine), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), NNK-d 4 (4-(methylnitrosamino)-1-(2,4,5,6-tetradeutero-3-pyridyl)-1-butanone, ()-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and ()-NNAL-d 3 (4-(trideuteromethyl-nitrosamino)-1-(3-pyridyl)-1-butanol were purchased from Toronto Research Chemicals (Ontario, Canada)

Essential safety equipment and smoke alarms are made to detect the presence of smoke particles in the air