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While Australia is widely regarded as a world-leader in tobacco control, Mr Harper pointed out that now was not the time to become complacent about our success

I was drinking and smoking at eight, and I once nearly burned the house down'

Lung function in people with COPD can decline substantially before symptoms become restrictive enough to disrupt daily life, meaning that by the time breathlessness noticeably affects routine activities, significant lung damage may already have occurred

Motor neuron diseases other than ALS, such as primary lateral sclerosis, progressive bulbar palsy, and spinal muscular atrophy, were excluded from the analysis