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If you have a pack of cigarettes a day, youre twice as likely to have a heart attack as someone who doesnt smoke

Tobacco-cannabis mixes were least popular in the Americas, with only 16% of Canadian, 4.4% of US, 6.9% of Mexican, and 7.4% of Brazilian cannabis users combining the two

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If you have angina or have had a heart attack, angioplasty or surgery may be the best treatment option

Study characteristics and included observations for all input data used in the analyses are also provided in the Supplementary Information, while the resulting estimates can also be found in Table 2, but they can all be found in the Burden of Proof tool described above