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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Harrell PT, Simmons VN, Correa JB, Padhya TA, Brandon TH

Cultural Impact The 500 Cigarettes meme gave *The Orville* one of its most recognizable pop culture moments outside the show's existing fanbase

Researchers at the Wellcome Trust Sanger Institute in the UK and Los Alamos National Laboratory in the US measured the catastrophic genetic damage caused by smoking in different organs of the body and identified several different mechanisms by which tobacco smoking causes mutations in DNA

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