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Recently Genazzani et al

In addition, among the fusion proteins, nGLP1-DARPin had a higher binding affinity to HSA (G = 9.2 kcal mol 1 ) compared to the mGLP1-DARPin-1 (G = 8.1 kcal mol 1 ) and mGLP1-DARPin-2 (G = 8.3 kcal mol 1 ) fusion proteins, which is comparable with the individual DARPin complexed with HSA (G = 9.6 kcal mol 1 )

(2021) 22(Suppl 4):e13254

Please note: No GLP-1 agentsingle or dualhas an FDA indication for AUD or OUD, so any use for cravings remains off-label