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Retention will be aided by compensation of up to $1,188 per participant for completion of assessments and remotely obsereved adherence to study medcation for V+BC and P+BC groups

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However, this has not been attributed to the variables that are known to increase the level of augmentation, like lower heart rate, increased arterial stiffness, or higher systemic vascular resistance 24,26,36,48,49,62 In our study present smokers had higher upright AIx, and higher supine and upright AIx@75, in the absence of changes in BP, heart rate, ejection duration, PWV, and systemic vascular resistance that could explain an increase in AIx

It's not just a physical addiction but also a psychological one, making it challenging to break the habit