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The interaction between alpha-synuclein and mitochondrial dysfunction in Parkinsons disease

Increased levels of saturated fatty acids (FFA) and glucose in the blood are considered to be major mediators of signals that bind -cells to apoptosis and death for T2 DM

Namely, redox-active metals, like Fe 2+ , react with peroxides generating highly active hydroxyl radicals (R-HO ) that further propagate the peroxidation reaction (43)

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