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In the non-psychiatric cohort, CHANTIX was not associated with an increased incidence of clinically significant neuropsychiatric adverse events in a composite endpoint comprising anxiety, depression, feeling abnormal, hostility, agitation, aggression, delusions, hallucinations, homicidal ideation, mania, panic, and irritability

It uses the transfer of heat or cold through solid metal to run the device

Differences for ONP/TFONP were smaller and sometimes non-significant, suggesting weaker smokernon-smoker separation for newer oral products