This reduction in central fat contributes to a slimmer waistline and a lower risk of type 2 diabetes, insulin resistance, and cardiovascular disease
Sideridou, I., Tserki, V
Moreover, there is evidence that both, oxidative stress and mitochondrial damage are associated with changes in GSH homeostasis
The Efficacy of GLP-1 Analogues on Appetite Parameters, Gastric Emptying, Food Preference and Taste Among Adults with Obesity: Systematic Review of Randomized Controlled Trials
Animal studies have demonstrated that continuous administration of IGF-1 can prevent cartilage degradation and promote repair, highlighting its potential as a treatment for osteoarthritis (Wen et al., 2021)
Dose selection for an elderly patient should be cautious, recognizing the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy and the higher risk of myopathy