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Hum Mol Genet 1999

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Multiple gut-hormone combinations have been explored preclinically, with an appreciable number having advanced to clinical studies, with unimolecular peptides possessing varying degrees of GLP-1R, GIPR, and GCGR activity constituting the clinically most matured set of drug candidates. Notable examples and future research GLP-1R/GCGR coagonists represented the first generation of multi-receptor interventions, including SAR425899, Mazdutide, Cotadutide, NN9277, and ALT-801

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That said, no study has directly tested this three-way combination