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These decisions require individualized clinical discussion, not a one-size-fits-all protocol

Metabolism and Functions

Diabetes Care 37 , 26402642 (2014)

Cardiovascular Risk The TRAVERSE trial (N=5,246), published in the New England Journal of Medicine in 2023, found that testosterone replacement did not increase the rate of major adverse cardiovascular events in middle-aged and older men with hypogonadism and high cardiovascular risk (HR 1.02, 95% CI 0.84 to 1.24)

The randomized controlled prospective medium-sized tumor trial involved 1317 treatment-naive patients with choroidal melanomas who were treated with enucleation (n=660) or iodine-125 plaque brachytherapy (n=657)

To address this, researchers are exploring alternative routes of administration , including oral, transdermal, and inhalable formulations