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Introduction Cigarette smoking is a major risk factor for the development of vascular diseases, such as atherosclerosis and pulmonary hypertension (1)

For some cigarettes, the levels are more than 20 times higher

Thus, theoretically we expect confounding of the tobacco-mortality association to increase over time (eg, by socioeconomic factors, and more proximally diet, physical activity and alcohol consumption)

Many exceptions exist

There is a need to continue promoting mental health support and implementing tailored interventions to combat all forms of tobacco use among adolescents.

"Compared to this, 50 yen is much cheaper." The three facilities are used by about 900 smokers in total per day