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The long lag time between tobacco exposure and cardiovascular disease makes it difficult to evaluate how newer products, such as e-cigarettes, affect cardiovascular health

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Cannabis is increasingly becoming legal in many regions, while certain drugs have approved medical applications but remain illegal for recreational use (such as opioids)

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Unknown Long-Term Effects: Vaping is a relatively new phenomenon, and the long-term health effects of e-cigarette use, including the potential risks to the developing fetus, are not well understood