Conclusion: The literature suggests anti-inflammatory effects of GLP-1RAs may provide direct benefit in the treatment of dermatologic conditions independent of glucose control in addition to indirect improvement via modulation of blood glucose and weight loss
However, indirect interactions warrant consideration: Gastrointestinal Effects: Wegovy commonly causes nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
106 GLP-1 is also generated similarly in the central nervous system
For some individuals, however, losing weight proves difficult due to various factors
When expressed as a percentage increase in comparison to a placebo (1.31mIU/l or 0.4ng/ml), this augmentation appears to surpass 60-fold
doi: 10.1126/science.1104816 10 BauerP