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However, to consume the same amount of creatine as you would from supplementation you would need to eat ~4-5kg of chicken/beef per day

However, the DPP/DPPOS 21-year follow-up did not find a statistically significant reduction in major cardiovascular events with metformin versus placebo, though favorable trends in risk factors were observed

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demonstrated that brain-specific BDNF conditional knockout mice present worse cardiac remodeling and function after MI compared with control mice suggesting a cardioprotective role of neuronal BDNF production after MI [55]