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Inflammatory cytokines like Tumor necrosis factor (TNF)-, chronically released in obesity, activate pathways that can lead to IR

Faour, M., Magnan, C., Gurden, H

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GLP-1 therapy is differentit targets underlying metabolic imbalance , which is why results tend to be stronger and longer-lasting when paired with clinician support

Targeting insulin resistance, reactive oxygen species, inflammation, programmed cell death, ER stress, and mitochondrial dysfunction for the therapeutic prevention of free fatty acid-induced vascular endothelial lipotoxicity

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