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Decreased interstitial cell of cajal volume in patients with slow-transit constipation

The time of day doesnt matter necessarily , but a morning injection would allow you to take advantage of MOTS-cs potentially energizing effects (and avoid an energy boost when youre heading to bed)

Fun fact: Centella has been used as a medicine and in food for many centuries

But they can cause a dangerous condition called serotonin syndrome if mixed with antidepressants, Suboxone, or other meds

This therapy rapidly reversed the hind legs failure after abdominal aorta anastomosis (Vukojevic et al., 2018) and inferior caval vein syndrome (Vukojevic et al., 2018)

(28) The adjusted hazard ratio for amputation did not significantly differ across drug classes