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doi:10.5694/j.1326-5377.2005.tb07070.x

Additional information supported that combustible tobacco products impaired vascular dilation while exposure to ENDS did not [116]

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Nicotine and tobacco constituents may promote hepatic steatosis by increasing insulin resistance and impairing liver fat metabolism

Bladder cancer risk increases with smoking duration (the number of years you have smoked) and intensity (the number of cigarettes smoked each day), although duration appears to have a greater effect