Keywords: Ulcerative colitis (UC), Genetic predisposition, Immune dysregulation, Alteration of intestinal flora, Biologic therapy, Herbal treatment Introduction Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that manifests with inflammation and ulcers in the colonic lining, resulting in a spectrum of symptoms including abdominal pain, diarrhea, rectal bleeding, tenesmus (a sense of pressure), and weight loss [1, 2]
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The insidious disease progression presents substantial clinical challenges, as approximately 2040% of NAFLD patients may develop non-alcoholic steatohepatitis (NASH) over several years (1, 2), which can subsequently advance to liver fibrosis and HCC (3)
Int J Endocrinol 2022(1):6999907