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[DOI] [PubMed] [Google Scholar] Ockelford P

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Higher-risk patients include those in the dose-escalation phase, those with nausea, vomiting, bloating, abdominal pain, early satiety, or reflux symptoms, those on higher doses with GI side effects, and those with known gastroparesis or other conditions that slow gastric emptying

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The previous study has reported that curcumin enhances the suppression of HDAC activity and inhibits HDAC8 activity of isoform, elevating the suppressors cytokine signaling expression (SOCS1, SOCS3) in the leukemic cell ( A more recent study confirms the inhibitory capacity of curcumin on HDACs