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Ethical approval The present study was conducted in accordance with the Declaration of Helsinki and approved by the Committee for Ethics in Scientific Research of Jan Dlugosz University in Czestochowa (document KE-U/9/2024 from the 4th of June 2024)

Additionally, zinc supports skin repair and protects against post-inflammatory hyperpigmentation, which can occur after acne or skin injuries

Strikingly, oxidative stress also promoted HO-1 translocation to mitochondria, leading to mitochondrial iron overload and lipid reactive oxygen species (ROS) accumulation

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A quick, honest caveat Every sign above is also seen in far more common conditions: iron-deficiency anaemia, hypothyroidism, poor sleep, vitamin D or B12 deficiency, and depression, among others

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