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Reports that metformin may inhibit autophagy (Huang et al., 2020) highlight the complexity of its regulation of mitochondrial homeostasis and underscore the need for further investigation

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Additionally SHH, together with MAPK and cJun cascades, has been shown to orchestrate differentiation of mature Schwann cells into repair entities in injured nerves (Moreau and Boucher, 2020), see also Table 1 and Figure 6