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Lee D, de Keizer N, Lau F, Cornet R

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Product Overview Discovery and Scientific Background 5-Amino-1MQ was identified during a structure-based drug-discovery campaign targeting NNMT, a cytosolic methyltransferase that catalyses transfer of a methyl group from SAM to nicotinamide (NAM), generating 1-methylnicotinamide (1-MNA)

Shi ZZ, Habib GM, Rhead WJ, Gahl WA, He X, Sazer S, Lieberman MW: Mutations in the glutathione synthetase gene cause 5-oxoprolinuria

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