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Systemic improvements

110 Treatment with 1,500 mg curcumin per day for 12 weeks was also shown to upregulate expression of a PPAR- activator molecule and improve markers of oxidative stress more than placebo in a controlled trial in 72 women with PCOS

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Similarly to methylated arginines, several clinical studies have shown that higher homocysteine concentrations independently predict adverse cardiovascular outcomes and improve risk reclassification [13][15]

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