Pyrazinamide 58856932 enzymatic cleavage by β-galactosidase yields

enzymatic cleavage by β-galactosidase yields an insoluble blue precipitate

ensuring complete denaturation prior to electrophoresis or mass spectrometry

solubility in H2O: soluble at 50 mg/ml

1-O-Methyl-glucoside

and buffer performance during method optimization

Pyrazinamide 58856932 enzymatic cleavage by β-galactosidase yieldsPyrazinamide is an anti tubercular antibiotic. It is also used to study ways to prevent liver toxicity and in the formation of polymeric copper complexes. Although the mechanism of action of pyrazinamide is not well understood, it is thought that upon entering a target cell, it is converted to pyrazinoic acid or POA. This conversion results in altered cellular permeability and decreased internal pH due to POA accumulation in the cytoplasm. This may