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I mean, the interaction only comes with which one is charged molecule, which one is not charged, right

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doi: 10.1371/journal.pone.0089270 113 MakTWGrusdatMDuncanGSDostertCNonnenmacherYCoxMet al

Conventional pharmacological treatments, such as opioid antagonists, dopamine (DA) reuptake inhibitors, and nicotinic partial agonists, target specific neurotransmitter systems involved in reinforcement and craving

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Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores