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In Treg cells, due to low expression of ABAT, GAB is not catabolized inside the cells and is exported to the extracellular compartment

doi: 10.2337/dc17-2510 4 ArtasensiAPedrettiAVistoliGFumagalliL

Reduces Appetite: GLP-1 acts on the brain to decrease appetite and increase feelings of satiety, which can lead to weight loss

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Glucagon receptor agonism can promote energy expenditure and fatty acid oxidation, potentially enhancing weight loss effects while maintaining glucose control