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2015;7(4):a017970
Enzymatic activity was evaluated by plotting Michaelis-Menten and Lineweaver-Burk graphs to calculate the V max and K m parameters
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Since liraglutide is not metabolized or eliminated by the kidneys or liver, its pharmacokinetics are not significantly affected by renal or hepatic dysfunction, providing a potential treatment advantage in patients with type 2 diabetes and concomitant kidney/liver disease [59]
Rat renal epinephrine synthesis
115 Drug therapies, however, pose risks of adverse side effects, which in some cases can include severe withdrawal symptoms
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