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Lnc-chop promotes immunosuppressive function of myeloid-derived suppressor cells in tumor and inflammatory environments

A2E intracellular accumulation enhances RPE photosensitization, generating high levels of both hydrogen peroxide (H 2 O 2 ) and superoxide anion (O 2 ) when the cells are exposed to blue-violet light, providing a possible cellular mechanism to explain the RPE dysfunction that causes AMD [5]

Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress (2003) 23:3394406

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Hepatoprotective effect of artichoke leaf extracts in comparison with silymarin on acetaminophen-induced hepatotoxicity in mice

It also activates mTORC1, stimulating protein synthesis and cell growth, and promotes glucose uptake via GLUT4 translocation