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However, conventional patches face significant challenges with peptide delivery due to the large molecular size of GLP-1 analogues, which is why many research approaches focus on microneedle technologies or advanced penetration enhancers

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The researchers encapsulated both pegylated IGF-1 mimics and control formulations (unpegylated IGF-1 mimics and rhIGF-1) within polycaprolactone-based matrices, enabling localized and sustained delivery to the repaired tendons

Role of Mitophagy in the pathogenesis of stroke: from mechanism to therapy